Beside their role as lipid solubilizers, bile acids (BAs) are increasingly appreciated as
signaling factors. As ligands of G-protein coupled receptors and nuclear hormone receptors
BAs control their own metabolism and act on lipid and energy metabolism. To study BA
function in detail, it is necessary to use methods for their quantification covering the
structural diversity of this group. Here we present a simple, sensitive liquid chromatography–
tandem mass spectrometry (LC–MS/MS) method for the analysis of bile acid profiles in …