[HTML][HTML] Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood
BK Chacko, PA Kramer, S Ravi, MS Johnson… - Laboratory …, 2013 - Elsevier
Peripheral blood mononuclear cells and platelets have long been recognized as having the
potential to act as sensitive markers for mitochondrial dysfunction in a broad range of
pathological conditions. However, the bioenergetic function of these cells has not been
examined from the same donors, yet this is important for the selection of cell types for
translational studies. Here, we demonstrate the measurement of cellular bioenergetics in
isolated human monocytes, lymphocytes, and platelets, including the oxidative burst from …
potential to act as sensitive markers for mitochondrial dysfunction in a broad range of
pathological conditions. However, the bioenergetic function of these cells has not been
examined from the same donors, yet this is important for the selection of cell types for
translational studies. Here, we demonstrate the measurement of cellular bioenergetics in
isolated human monocytes, lymphocytes, and platelets, including the oxidative burst from …