A switching control law approach for cancer immunotherapy of an evolutionary tumor growth model

AI Doban, M Lazar - Mathematical biosciences, 2017 - Elsevier
We propose a new approach for tumor immunotherapy which is based on a switching
control strategy defined on domains of attraction of equilibria of interest. For this, we
consider a recently derived model which captures the effects of the tumor cells on the
immune system and viceversa, through predator–prey competition terms. Additionally, it
incorporates the immune system's mechanism for producing hunting immune cells, which
makes the model suitable for immunotherapy strategies analysis and design. For computing …