The presence of plasma proteins in the tubular lumen has variety of adverse effects on the
tubular cells. Among various plasma proteins filtered through glomerular barrier,
complement has been proven as the possible candidate inducing tubulointerstitial injury. To
study the role of intratubular complement activation in proteinuric patients, complement
activation products (CAP) at C3 level (iC3b and Bb) and C9 level (membrane attack
complex) were measured in both plasma and urine of patients with minimal change …