White adipose tissue (WAT) is a dynamic and modifiable tissue that develops late during
gestation in humans and through early postnatal development in rodents. WAT is unique in
that it can account for as little as 3% of total body weight in elite athletes or as much as 70%
in the morbidly obese. With the development of obesity, WAT undergoes a process of tissue
remodeling in which adipocytes increase in both number (hyperplasia) and size
(hypertrophy). Metabolic derangements associated with obesity, including type 2 diabetes …