Variants in the engulfment and cell motility 1 gene, ELMO1, have previously been
associated with kidney disease attributed to type 2 diabetes. The Pima Indians of Arizona
have high rates of diabetic nephropathy, which is strongly dependent on genetic
determinants; thus, we sought to investigate the role of ELMO1 polymorphisms in mediating
susceptibility to this disease in this population. Genotype distributions were compared
among 141 individuals with nephropathy and 416 individuals without heavy proteinuria in a …