Cytoskeleton scaffold in cardiac myocytes provides structural support and
compartmentalization of intracellular components. It is implicated in cardiac pathologies
including hypertrophy and failure, playing a key role in the determinism of contractile and
diastolic dysfunctions. Chromogranin A (CgA) and its derived peptides have revealed
themselves as novel cardiovascular modulators. In humans, normal CgA levels considerably
increase in several pathologies, including heart failure. Recent data have shown on the …