A unique microvascular phenotype shared by juvenile hemangiomas and human placenta

PE North, M Waner, A Mizeracki, RE Mrak… - Archives of …, 2001 - jamanetwork.com
Background Juvenile hemangiomas are common, benign tumors, distinctive for their
perinatal presentation, rapid growth during the first year of life, and subsequent involution.
We recently reported that endothelia of hemangiomas highly express GLUT1, a glucose
transporter normally restricted to endothelia with blood-tissue barrier function, as in brain
and placenta. Objective To investigate possible further similarities between hemangioma
and placental vessels. Design In a retrospective study of a variety of vascular tumors and …