Remission of proteinuria improves prognosis in IgA nephropathy
HN Reich, JW Scholey, DC Cattran - Journal of the American …, 2007 - journals.lww.com
Proteinuria has been shown to be an adverse prognostic factor in IgA nephropathy. The
benefit of achieving a partial remission of proteinuria, however, has not been well described.
We studied 542 patients with biopsy-proven primary IgA nephropathy in the Toronto
Glomerulonephritis Registry and found that glomerular filtration rate (GFR) declined at−
0.38±0.61 ml/min per 1.73 m 2/mo overall, with 30% of subjects reaching end-stage renal
disease. Multivariate analysis revealed that proteinuria during follow-up was the most …
benefit of achieving a partial remission of proteinuria, however, has not been well described.
We studied 542 patients with biopsy-proven primary IgA nephropathy in the Toronto
Glomerulonephritis Registry and found that glomerular filtration rate (GFR) declined at−
0.38±0.61 ml/min per 1.73 m 2/mo overall, with 30% of subjects reaching end-stage renal
disease. Multivariate analysis revealed that proteinuria during follow-up was the most …