[HTML][HTML] Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies

MU Jakobsen, EJ O'Reilly, BL Heitmann… - The American journal of …, 2009 - Elsevier
Background Saturated fatty acid (SFA) intake increases plasma LDL-cholesterol
concentrations; therefore, intake should be reduced to prevent coronary heart disease
(CHD). Lower habitual intakes of SFAs, however, require substitution of other macronutrients
to maintain energy balance. Objective: We investigated associations between energy intake
from monounsaturated fatty acids (MUFAs), polyunsaturated fatty acids (PUFAs), and
carbohydrates and risk of CHD while assessing the potential effect-modifying role of sex and …