CD8 T cell persistence in treated HIV infection
JC Mudd, MM Lederman - Current Opinion in HIV and AIDS, 2014 - journals.lww.com
JC Mudd, MM Lederman
Current Opinion in HIV and AIDS, 2014•journals.lww.comCirculating CD8 T cell numbers remain abnormally elevated in many treated HIV-infected
patients and this elevation is associated with adverse clinical events. Future studies will be
needed to assess the mechanisms of CD8 T cell expansion and to define the role of CD8
lymphocytosis in the clinical course of treated HIV disease.
patients and this elevation is associated with adverse clinical events. Future studies will be
needed to assess the mechanisms of CD8 T cell expansion and to define the role of CD8
lymphocytosis in the clinical course of treated HIV disease.
Summary
Circulating CD8 T cell numbers remain abnormally elevated in many treated HIV-infected patients and this elevation is associated with adverse clinical events. Future studies will be needed to assess the mechanisms of CD8 T cell expansion and to define the role of CD8 lymphocytosis in the clinical course of treated HIV disease.
Lippincott Williams & Wilkins