Epigenetics: a new way to look at kidney diseases

P Beckerman, YA Ko, K Susztak - Nephrology Dialysis …, 2014 - academic.oup.com
P Beckerman, YA Ko, K Susztak
Nephrology Dialysis Transplantation, 2014academic.oup.com
Only a few percent of the 3 billion pairs of chemical letters in the human genome is
responsible for protein-coding sequences. Recent advances in the field of epigenomics
have helped us to understand how most of the remaining sequences are responsible for
gene regulation at baseline and in disease conditions. Here we discuss recent advances in
the area of epigenetics—specifically in cytosine modifications—and its application in the
field of nephrology.
Abstract
Only a few percent of the 3 billion pairs of chemical letters in the human genome is responsible for protein-coding sequences. Recent advances in the field of epigenomics have helped us to understand how most of the remaining sequences are responsible for gene regulation at baseline and in disease conditions. Here we discuss recent advances in the area of epigenetics—specifically in cytosine modifications—and its application in the field of nephrology.
Oxford University Press