Association of reduced glyoxalase 1 activity and painful peripheral diabetic neuropathy in type 1 and 2 diabetes mellitus patients
E Skapare, I Konrade, E Liepinsh, I Strele… - Journal of Diabetes and …, 2013 - Elsevier
AIMS: The present study was undertaken to investigate the relationship between glyoxalase
1 (Glo1) enzyme activity and painful diabetic neuropathy (DN) in patients with diabetes
mellitus. METHODS: Glo1 activity and biochemical markers were determined in blood
samples from 108 patients with type 1 diabetes, 109 patients with type 2 diabetes, and 132
individuals without diabetes as a control. Painful and painless peripheral DN was assessed
and multivariate regression analysis was used to determine independent association of …
1 (Glo1) enzyme activity and painful diabetic neuropathy (DN) in patients with diabetes
mellitus. METHODS: Glo1 activity and biochemical markers were determined in blood
samples from 108 patients with type 1 diabetes, 109 patients with type 2 diabetes, and 132
individuals without diabetes as a control. Painful and painless peripheral DN was assessed
and multivariate regression analysis was used to determine independent association of …