Studying diabetes through the eyes of a fish: microdissection, visualization, and analysis of the adult tg (fli: EGFP) zebrafish retinal vasculature

LM Wiggenhauser, K Kohl, N Dietrich… - JoVE (Journal of …, 2017 - jove.com
Diabetic retinopathy is the leading cause of blindness among middle-aged adults. The rising
prevalence of diabetes worldwide will make the prevention of diabetic microvascular
complications one of the key research fields of the next decades. Specialized, targeted
therapy and novel therapeutic drugs are needed to manage the increasing number of
patients at risk of vision-loss. The zebrafish is an established animal model for
developmental research questions with increasing relevance for modeling metabolic …