[HTML][HTML] Late graft failure after kidney transplantation as the consequence of late versus early events
RS Gaston, A Fieberg, L Hunsicker, BL Kasiske… - American Journal of …, 2018 - Elsevier
Beyond the first posttransplant year, 3% of kidney transplants fail annually. In a prospective,
multicenter cohort study, we tested the relative impact of early versus late events on risk of
long-term death-censored graft failure (DCGF). In grafts surviving at least 90 days, early
events (acute rejection [AR] and delayed graft function [DGF] before day 90) were recorded;
serum creatinine (Cr) at day 90 was defined as baseline. Thereafter, a 25% rise in serum Cr
or new-onset proteinuria triggered graft biopsy (index biopsy, IBx), allowing comparison of …
multicenter cohort study, we tested the relative impact of early versus late events on risk of
long-term death-censored graft failure (DCGF). In grafts surviving at least 90 days, early
events (acute rejection [AR] and delayed graft function [DGF] before day 90) were recorded;
serum creatinine (Cr) at day 90 was defined as baseline. Thereafter, a 25% rise in serum Cr
or new-onset proteinuria triggered graft biopsy (index biopsy, IBx), allowing comparison of …