Improving long-term graft survival remains one of the critical challenges facing kidney
transplantation since a great portion of kidney grafts are lost by 10 years after
transplantation. Understanding the causes of chronic allograft injury and providing timely
therapeutic interventions are essential for improving these outcomes. In this review, we will
discuss the recent data that emerged turning down calcineurin inhibitors as the primary
cause of long-term graft injury and highlighting the increased importance of non-compliance …