[HTML][HTML] HLA-DR and-DQ eplet mismatches and transplant glomerulopathy: a nested case–control study

R Sapir-Pichhadze, K Tinckam, K Quach… - American journal of …, 2015 - Elsevier
We conducted a nested case–control study from a cohort of adult kidney transplant
recipients to assess the risk of transplant glomerulopathy (TG) as a function of donor and
recipient HLA-DR and-DQ incompatibility at the eplet level. Cases (n= 52) were defined as
patients diagnosed with transplant glomerulopathy based on biopsies showing glomerular
basement membrane duplication without immune complex deposition. Controls (n= 104)
with a similar follow-up from transplantation were randomly selected from the remaining …