One of the most common hematologic malignancies in adults, myelodysplastic syndrome
(MDS) is a heterogenous group of clonal disorders characterized by peripheral cytopenia (s)
and normal or hypercellular bone marrow with dysplasia in≥ 1 blood cell lineages. MDS
frequently evolves to secondary acute myeloid leukemia with poor prognosis. Although
uncommon among pediatric hematologic malignancies, both de novo and secondary MDS
occur in children and may be the first presentation of an inherited bone marrow failure …