Complete genome sequence of a tenth human polyomavirus

CB Buck, GQ Phan, MT Raiji, PM Murphy… - 2012 - Am Soc Microbiol
CB Buck, GQ Phan, MT Raiji, PM Murphy, DH McDermott, AA McBride
2012Am Soc Microbiol
Nine polyomavirus (PyV) species are known to productively infect humans. The circular DNA
genomes of PyVs are readily detectable using rolling circle amplification (RCA). RCA-based
analysis of condyloma specimens from a patient with w arts, h ypogammaglobulinemia, i
nfections, and m yelokathexis (WHIM) syndrome demonstrated the presence of a tenth
apparently human-tropic polyomavirus species, which we name HPyV10.
Abstract
Nine polyomavirus (PyV) species are known to productively infect humans. The circular DNA genomes of PyVs are readily detectable using rolling circle amplification (RCA). RCA-based analysis of condyloma specimens from a patient with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome demonstrated the presence of a tenth apparently human-tropic polyomavirus species, which we name HPyV10.
American Society for Microbiology