Patients with sporadic colorectal cancer or advanced adenomatous polyp have elevated anti-JC virus antibody titer in comparison with healthy controls: a cross …

Y Niv, A Vilkin, Z Levi - Journal of clinical gastroenterology, 2010 - journals.lww.com
Objective JC virus (JCV) is thought to infect approximately 80% of the human population.
Antibodies against JCV can be found in the sera of many people with and without colorectal
carcinoma (CRC). We hypothesized that JCV antibody titer will be higher in CRC patients
than in healthy controls. Aim To evaluate this hypothesis in a cohort of patients undergoing
colonoscopy. We compared JCV antibody titers in patients with simple adenoma, advanced
adenomatous polyp (AAP), CRC, and healthy controls, and evaluated JCV DNA in the …