[HTML][HTML] Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding
MFF Chong, L Hodson, AS Bickerton, R Roberts… - The American journal of …, 2008 - Elsevier
Background High-carbohydrate (HC) diets increase de novo lipogenesis (DNL), but effects
on stearoyl-CoA desaturase (SCD) are not so well studied. Objective The objective was to
investigate DNL and SCD in liver and adipose tissue by using fatty acid ratios after short-
term dietary intervention. Design Eight subjects consumed isoenergetic 3-d HC (10% fat;
75% carbohydrates) or higher fat (HF; 40% fat; 45% carbohydrates) diets (sugar to starch
ratio: 60: 40 for both) in a crossover study. Blood was taken from an artery and a vein …
on stearoyl-CoA desaturase (SCD) are not so well studied. Objective The objective was to
investigate DNL and SCD in liver and adipose tissue by using fatty acid ratios after short-
term dietary intervention. Design Eight subjects consumed isoenergetic 3-d HC (10% fat;
75% carbohydrates) or higher fat (HF; 40% fat; 45% carbohydrates) diets (sugar to starch
ratio: 60: 40 for both) in a crossover study. Blood was taken from an artery and a vein …