Cancer in primary immunodeficiency diseases: cancer incidence in the United States Immune Deficiency Network Registry

PC Mayor, KH Eng, KL Singel, SI Abrams… - Journal of allergy and …, 2018 - Elsevier
Background We evaluated the overall and site-specific incidence of cancer in subjects with
primary immunodeficiency diseases (PIDD) enrolled in the United States Immune Deficiency
Network (USIDNET) registry compared with age-adjusted cancer incidence in the
Surveillance, Epidemiology and End Results Program (SEER) database. Objective We
hypothesized that subjects with PIDD would have an increased incidence of cancer due to
impaired immune function. Methods Overall and site-specific cancer incidence rates were …