Hematopoietic stem cell transplantation outcomes for 11 patients with dedicator of cytokinesis 8 deficiency
W Al-Herz, JI Chu, J van der Spek… - Journal of Allergy and …, 2016 - Elsevier
Background Dedicator of cytokinesis 8 (DOCK8) deficiency can be cured by allogeneic
hematopoietic stem cell transplantation (HSCT). Reports of outcomes are still limited.
Objective We sought to analyze the results of HSCT in patients with DOCK8 deficiency and
report whether approaches resulting in mixed chimerism result in clinically relevant immune
reconstitution. Methods We performed a retrospective chart review of 11 patients with
DOCK8 deficiency and measured DOCK8 expression and cytokine production. Results Of …
hematopoietic stem cell transplantation (HSCT). Reports of outcomes are still limited.
Objective We sought to analyze the results of HSCT in patients with DOCK8 deficiency and
report whether approaches resulting in mixed chimerism result in clinically relevant immune
reconstitution. Methods We performed a retrospective chart review of 11 patients with
DOCK8 deficiency and measured DOCK8 expression and cytokine production. Results Of …
