Hyperkalemia is common in patients with impaired kidney function or who take drugs that
inhibit the renin-angiotensin-aldosterone axis. During the past decade, substantial advances
in understanding how the body controls potassium excretion have been made, which may
lead to improved standard of care for these patients. Renal potassium disposition is primarily
handled by a short segment of the nephron, comprising part of the distal convoluted tubule
and the connecting tubule, and regulation results from the interplay between aldosterone …