Successful lung transplantation after donor lung reconditioning with urokinase in ex vivo lung perfusion system

I Inci, Y Yamada, S Hillinger, W Jungraithmayr… - The Annals of thoracic …, 2014 - Elsevier
I Inci, Y Yamada, S Hillinger, W Jungraithmayr, M Trinkwitz, W Weder
The Annals of thoracic surgery, 2014Elsevier
Acute pulmonary embolism is considered a contraindication to lung donation for
transplantation as it might result in graft dysfunction. Ex vivo lung perfusion (EVLP) is a novel
method to assess and recondition a questionable donor graft before transplantation. In this
report we present a case of successful bilateral lung transplant after donor lung assessment
and treatment with a fibrinolytic agent, urokinase, during EVLP.
Acute pulmonary embolism is considered a contraindication to lung donation for transplantation as it might result in graft dysfunction. Ex vivo lung perfusion (EVLP) is a novel method to assess and recondition a questionable donor graft before transplantation. In this report we present a case of successful bilateral lung transplant after donor lung assessment and treatment with a fibrinolytic agent, urokinase, during EVLP.
Elsevier