The ketogenic diet (KD) is a high-fat, low carbohydrate diet that is used as a therapy for
intractable epilepsy. However, the mechanism (s) by which the KD achieves neuroprotection
and/or seizure control are not yet known. The broad efficacy of the KD in diverse epilepsies
coupled with its profound influence on metabolism suggests that mitochondrial functions
may be critical in its mechanism (s) of seizure control. Mitochondria subserve important
cellular functions that include the production of cellular ATP, control of apoptosis …