Analyses of shared genetic factors between asthma and obesity in children

E Melén, BE Himes, JM Brehm, N Boutaoui… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Epidemiologic studies consistently show associations between asthma and
obesity. Shared genetics might account for this association. OBJECTIVE: We sought to
identify genetic variants associated with both asthma and obesity. METHODS: On the basis
of a literature search, we identified genes from (1) genome-wide association studies
(GWASs) of body mass index (BMI; n= 17 genes),(2) GWASs of asthma (n= 14), and (3)
candidate gene studies of BMI and asthma (n= 7). We used GWAS data from the Childhood …