Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans
H Wu, I Romieu, M Shi, DB Hancock, H Li… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: More than 200 asthma candidate genes have been examined in human
association studies or identified with knockout mouse approaches. However, many have not
been systematically replicated in human populations, especially those containing a large
number of tagging single nucleotide polymorphisms (SNPs). OBJECTIVE: We
comprehensively evaluated the association of previously implicated asthma candidate
genes with childhood asthma in a Mexico City population. METHODS: From the literature …
association studies or identified with knockout mouse approaches. However, many have not
been systematically replicated in human populations, especially those containing a large
number of tagging single nucleotide polymorphisms (SNPs). OBJECTIVE: We
comprehensively evaluated the association of previously implicated asthma candidate
genes with childhood asthma in a Mexico City population. METHODS: From the literature …