Biochemical large-scale identification of MHC class I ligands
DJ Kowalewski, S Stevanović - Antigen Processing: Methods and …, 2013 - Springer
DJ Kowalewski, S Stevanović
Antigen Processing: Methods and Protocols, 2013•SpringerThe large-scale identification of MHC class I presented peptides is indispensable for gaining
insight into the fundamental rules of immune recognition as well as it is an invaluable tool in
identifying potential targets for the immunotherapy of disease. In this chapter we briefly
review the existing strategies for the analysis of MHC ligandomes and provide an in-depth
protocol for the immunoaffinity purification of MHC class I presented peptides from primary
tissues or cells.
insight into the fundamental rules of immune recognition as well as it is an invaluable tool in
identifying potential targets for the immunotherapy of disease. In this chapter we briefly
review the existing strategies for the analysis of MHC ligandomes and provide an in-depth
protocol for the immunoaffinity purification of MHC class I presented peptides from primary
tissues or cells.
Abstract
The large-scale identification of MHC class I presented peptides is indispensable for gaining insight into the fundamental rules of immune recognition as well as it is an invaluable tool in identifying potential targets for the immunotherapy of disease. In this chapter we briefly review the existing strategies for the analysis of MHC ligandomes and provide an in-depth protocol for the immunoaffinity purification of MHC class I presented peptides from primary tissues or cells.
Springer