Therapeutic cancer vaccines: past, present, and future

C Guo, MH Manjili, JR Subjeck, D Sarkar… - Advances in cancer …, 2013 - Elsevier
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results
from clinical trials recently led to the approval of the first therapeutic cancer vaccine by the
US Food and Drug Administration. This major breakthrough not only provides a new
treatment modality for cancer management but also paves the way for rationally designing
and optimizing future vaccines with improved anticancer efficacy. Numerous vaccine …