Coinfections naturally occur due to the geographic overlap of distinct types of pathogenic
organisms. Concurrent infections most likely modulate the respective immune response to
each single pathogen and may thereby affect pathogenesis and disease outcome.
Coinfected patients may also respond differentially to anti-infective interventions. Coinfection
between tuberculosis as caused by mycobacteria and the malaria parasite Plasmodium,
both of which are coendemic in many parts of sub-Saharan Africa, has not been studied in …