Clinical gram-positive sepsis: does it fundamentally differ from gram-negative bacterial sepsis?
SM Opal, J Cohen - Critical care medicine, 1999 - journals.lww.com
Objective To review the basic differences between Gram-positive and Gram-negative sepsis
and to assess the effect of these differences on current and future therapeutic strategies for
sepsis. Design Literature review of the past 30 yrs of laboratory and clinical reports that
analyze the microbial aspects of sepsis and the immunologic response to systemic infection.
Results The increasing prevalence of sepsis from Gram-positive bacterial pathogens
necessitates reevaluation of many of the basic assumptions about the molecular …
and to assess the effect of these differences on current and future therapeutic strategies for
sepsis. Design Literature review of the past 30 yrs of laboratory and clinical reports that
analyze the microbial aspects of sepsis and the immunologic response to systemic infection.
Results The increasing prevalence of sepsis from Gram-positive bacterial pathogens
necessitates reevaluation of many of the basic assumptions about the molecular …