Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity
C Walker, MK Kaegi, P Braun, K Blaser - Journal of Allergy and Clinical …, 1991 - Elsevier
Activated T-lymphocytes may regulate the eosinophilic inflammation of bronchial asthma. In
the present study, we investigated T cell activation and eosinophilia in blood and
bronchoalveolar lavage (BAL) in 17 patients with asthma not receiving steroid treatment.
Compared to normal individuals, BAL from patients with asthma contained significantly
increased numbers of both lymphocytes and eosinophils (EOSs). The lymphocytosis
consisted of increased numbers of both CD4+ and CD8+ T cells, and these T cell …
the present study, we investigated T cell activation and eosinophilia in blood and
bronchoalveolar lavage (BAL) in 17 patients with asthma not receiving steroid treatment.
Compared to normal individuals, BAL from patients with asthma contained significantly
increased numbers of both lymphocytes and eosinophils (EOSs). The lymphocytosis
consisted of increased numbers of both CD4+ and CD8+ T cells, and these T cell …