Associations between timing of corticosteroid treatment initiation and clinical outcomes in Duchenne muscular dystrophy
S Kim, Y Zhu, PA Romitti, DJ Fox, DW Sheehan… - Neuromuscular …, 2017 - Elsevier
The long-term efficacy of corticosteroid treatment and timing of treatment initiation among
Duchenne muscular dystrophy (DMD) patients is not well-understood. We used data from a
longitudinal, population-based DMD surveillance program to examine associations between
timing of treatment initiation (early childhood [before or at age 5 years], late childhood [after
age 5 years], and naïve [not treated]) and five clinical outcomes (age at loss of ambulation;
ages at onset of cardiomyopathy, scoliosis, and first fracture; and pulmonary function) …
Duchenne muscular dystrophy (DMD) patients is not well-understood. We used data from a
longitudinal, population-based DMD surveillance program to examine associations between
timing of treatment initiation (early childhood [before or at age 5 years], late childhood [after
age 5 years], and naïve [not treated]) and five clinical outcomes (age at loss of ambulation;
ages at onset of cardiomyopathy, scoliosis, and first fracture; and pulmonary function) …