This is a historical review of the contribution of the Framingham Heart Study to our
understanding of the epidemiology of blood pressure (BP) and cardiovascular disease
(CVD). Framingham investigators initially explored the epidemiological relationship of
various BP components to coronary heart disease in men and women and how this risk is
further modified by age, that is, how diastolic blood pressure (DBP) is the stronger predictor
of coronary heart disease risk in young people versus systolic blood pressure (SBP) in …