Entropy and enthalpy of polyelectrolyte complexation: Langevin dynamics simulations
Z Ou, M Muthukumar - The Journal of chemical physics, 2006 - pubs.aip.org
Electrostatic attraction between two oppositely charged polyelectrolytes results in
polyelectrolyte complexes widely used for flocculation, coating, and coacervation. 1
Recently, polyelectrolyte complexes have attracted considerable interest in the design of
cationic polymers as nonviral synthetic vectors for gene therapy purposes. 2, 3 Cationic
polymers “vectors” interact electrostatically with negatively charged DNA molecules,
condensing them into a globule that facilitates the transportation to targeted cells. Another …
polyelectrolyte complexes widely used for flocculation, coating, and coacervation. 1
Recently, polyelectrolyte complexes have attracted considerable interest in the design of
cationic polymers as nonviral synthetic vectors for gene therapy purposes. 2, 3 Cationic
polymers “vectors” interact electrostatically with negatively charged DNA molecules,
condensing them into a globule that facilitates the transportation to targeted cells. Another …