A comprehensive analysis of PAX8 expression in human epithelial tumors

AR Laury, R Perets, H Piao, JF Krane… - The American journal …, 2011 - journals.lww.com
PAX8 is a paired-box gene important in embryogenesis of the thyroid, Müllerian, and
renal/upper urinary tracts, and expression of PAX8 has been previously described in
carcinomas from each of these sites. However, a large study including a wide variety of
epithelial neoplasms from multiple organ sites other than the thyroid, kidney, or Müllerian
system has not been performed. The goal of this study was to evaluate the utility of PAX8
immunostaining based on the evaluation of a wide range of epithelial tumors. PAX8 …