Epigenetics in cancer
M Esteller - New England Journal of Medicine, 2008 - Mass Medical Soc
New England Journal of Medicine, 2008•Mass Medical Soc
Gene transcription can be activated or inhibited by a reversible modification of the gene; this
modification is termed an epigenetic change. This account of epigenetics in cancer reviews
the mechanisms and consequences of epigenetic changes in cancer cells and concludes
with the implications of these changes for the diagnosis, prognosis, and treatment of cancer.
modification is termed an epigenetic change. This account of epigenetics in cancer reviews
the mechanisms and consequences of epigenetic changes in cancer cells and concludes
with the implications of these changes for the diagnosis, prognosis, and treatment of cancer.
Gene transcription can be activated or inhibited by a reversible modification of the gene; this modification is termed an epigenetic change. This account of epigenetics in cancer reviews the mechanisms and consequences of epigenetic changes in cancer cells and concludes with the implications of these changes for the diagnosis, prognosis, and treatment of cancer.
The New England Journal Of Medicine