Systemic symptoms in the progression of cutaneous to systemic lupus erythematosus

IT Wieczorek, KJ Propert, J Okawa… - JAMA dermatology, 2014 - jamanetwork.com
Importance Patients with cutaneous lupus erythematosus (CLE) who develop systemic lupus
erythematosus (SLE) may have few and mild systemic symptoms. Objective To characterize
the types and severity of systemic symptoms in a longitudinal cohort of patients with CLE.
Design, Setting, and Participants Prospective, longitudinal cohort study of 77 patients with
CLE who presented between January 2007 and April 2011 at a university autoimmune skin
disease clinic. Main Outcomes and Measures Systemic symptoms and severity were …