[HTML][HTML] Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain
B Heller, E Adu-Gyamfi, W Smith-Kinnaman… - Journal of Biological …, 2010 - ASBMB
Polarity proteins promote the asymmetric organization of cells by orienting intracellular
sorting mechanisms, such as protein trafficking and cytoskeletal assembly. The localization
of individual polarity proteins in turn is often determined by association with factors that
mediate contact with other cells or the substratum. This arrangement for the Par and Crb
apical polarity complexes at the tight junction is disrupted by the adaptor protein Amot. Amot
directly binds the scaffolding proteins Patj and Mupp1 and redistributes them and their …
sorting mechanisms, such as protein trafficking and cytoskeletal assembly. The localization
of individual polarity proteins in turn is often determined by association with factors that
mediate contact with other cells or the substratum. This arrangement for the Par and Crb
apical polarity complexes at the tight junction is disrupted by the adaptor protein Amot. Amot
directly binds the scaffolding proteins Patj and Mupp1 and redistributes them and their …