There is no established modality to repair kidney damage resulting from ischemia-
reperfusion injury (IRI). Early responses to IRI involve lymphocytes, but the role of B cells in
tissue repair after IRI is unknown. Here, we examined B cell trafficking into postischemic
mouse kidneys and compared the repair response between control (wild-type) and μMT (B
cell-deficient) mice with and without adoptive transfer of B cells. B cells infiltrated
postischemic kidneys and subsequently activated and differentiated to plasma cells during …