Implantable insulin pump vs multiple-dose insulin for non—insulin-dependent diabetes mellitus: a randomized clinical trial

CD Saudek, WC Duckworth, A Giobbie-Hurder… - Jama, 1996 - jamanetwork.com
Objective.—To determine whether implantable insulin pump (IIP) therapy and multiple daily
insulin (MDI) injections could equally attain improved blood glucose control, and to compare
the 2 treatments with respect to reducing daily blood glucose fluctuations, reducing serious
hypoglycemic insulin reactions, and improving patients' quality of life. Design.—Randomized
clinical trial. Setting.—Seven Veterans Affairs medical centers. Patients.—One hundred
twenty-one male type II diabetic patients between the ages of 40 and 69 years, receiving at …