Labile plasma iron (LPI) represents a component of non-transferrin-bound iron (NTBI) that is
both redox-active and chelatable, capable of permeating into organs and inducing tissue
iron overload. It appears in various types of hemosiderosis (transfusional and non-
transfusional) and in other iron-overload conditions. Sustained levels of LPI could over time
compromise organ (eg heart) function and patient survival. With the advent of methods for
measuring LPI in the clinical setting, it has become possible to assess the implications of LPI …