Protein binding of 99Tcm-DTPA compared with other GFR tracers

M Rehling, LE Nielsen… - Nuclear medicine …, 2001 - journals.lww.com
Abstract 99 Tc m-Diethylenetriaminepentaacetic acid (99 Tc m-DTPA) has been postulated
to be more bound to plasma proteins than are other radiopharmaceuticals used for
measurement of glomerular filtration rate (GFR). The results of protein binding experiments
are, however, highly related to methodology. The aim of the present study was to compare
the protein binding of the 99 Tc m-DTPA preparation we use in our daily routine with that of
the other five 99 Tc m-DTPA preparations available and with other GFR tracers by using the …