[HTML][HTML] Complete regression of metastatic cervical cancer after treatment with human papillomavirus–targeted tumor-infiltrating T cells

S Stevanović, LM Draper, MM Langhan… - Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
S Stevanović, LM Draper, MM Langhan, TE Campbell, ML Kwong, JR Wunderlich…
Journal of Clinical Oncology, 2015ncbi.nlm.nih.gov
Purpose Metastatic cervical cancer is a prototypical chemotherapy-refractory epithelial
malignancy for which better treatments are needed. Adoptive T-cell therapy (ACT) is
emerging as a promising cancer treatment, but its study in epithelial malignancies has been
limited. This study was conducted to determine if ACT could mediate regression of
metastatic cervical cancer.
Abstract
Purpose
Metastatic cervical cancer is a prototypical chemotherapy-refractory epithelial malignancy for which better treatments are needed. Adoptive T-cell therapy (ACT) is emerging as a promising cancer treatment, but its study in epithelial malignancies has been limited. This study was conducted to determine if ACT could mediate regression of metastatic cervical cancer.
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