Genome sequence of the anterograde-spread-defective herpes simplex virus 1 strain MacIntyre
Genome Announcements, 2014•journals.asm.org
We used paired-end Illumina deep sequencing and de novo assembly to determine the
genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The
MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a
unique limitation in its neuronal spread, moving solely in the retrograde direction.
genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The
MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a
unique limitation in its neuronal spread, moving solely in the retrograde direction.
Abstract
We used paired-end Illumina deep sequencing and de novo assembly to determine the genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a unique limitation in its neuronal spread, moving solely in the retrograde direction.
American Society for Microbiology