[HTML][HTML] GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
Identification of protein phosphorylation sites with their cognate protein kinases (PKs) is a
key step to delineate molecular dynamics and plasticity underlying a variety of cellular
processes. Although nearly 10 kinase-specific prediction programs have been developed,
numerous PKs have been casually classified into subgroups without a standard rule. For
large scale predictions, the false positive rate has also never been addressed. In this work,
we adopted a well established rule to classify PKs into a hierarchical structure with four …
key step to delineate molecular dynamics and plasticity underlying a variety of cellular
processes. Although nearly 10 kinase-specific prediction programs have been developed,
numerous PKs have been casually classified into subgroups without a standard rule. For
large scale predictions, the false positive rate has also never been addressed. In this work,
we adopted a well established rule to classify PKs into a hierarchical structure with four …