Apolipoprotein AI, A-II, and VLDL-B-100 metabolism in men: comparison of a low-fat diet and a high-monounsaturated fatty acid diet

S Desroches, ME Paradis, M Pérusse, WR Archer… - Journal of lipid …, 2004 - ASBMB
The impact of a low-fat diet and a high-MUFA diet on apolipoprotein AI (apoA-I), apoA-II, and
VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was
compared in 65 men randomly assigned to one of two predefined experimental diets. A
subsample of 18 men participated in the kinetic study. Before and after the 6–7 week dietary
intervention, kinetic subjects received a primed-constant infusion of [5, 5, 5-2 H 3] l-leucine
for 12 h under feeding conditions. ApoA-I production rate (PR;− 31.5%; P< 0.001) and …