Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OmniHeart randomized trial

LJ Appel, FM Sacks, VJ Carey, E Obarzanek, JF Swain… - Jama, 2005 - jamanetwork.com
ContextReduced intake of saturated fat is widely recommended for prevention of
cardiovascular disease. The type of macronutrient that should replace saturated fat remains
uncertain. ObjectiveTo compare the effects of 3 healthful diets, each with reduced saturated
fat intake, on blood pressure and serum lipids. Design, Setting, and ParticipantsRandomized
, 3-period, crossover feeding study (April 2003 to June 2005) conducted in Baltimore, Md,
and Boston, Mass. Participants were 164 adults with prehypertension or stage 1 …