[HTML][HTML] Recovery of functional memory T cells in lung transplant recipients following induction therapy with alemtuzumab
Profound T-cell depletion with the monoclonal antibody alemtuzumab facilitates reduced
maintenance immunosuppression in abdominal and lung transplantation. While the
phenotype of the post-depletional T cells has been characterized, little is known about their
function. In the present study, global and CMV-specific T-cell function was assessed
longitudinally in 23 lung transplant (LTx) recipients using T-cell assays (ImmuKnow® and T
Cell Memory™, Cylex, Columbia, MD) during the first year posttransplant after induction …
maintenance immunosuppression in abdominal and lung transplantation. While the
phenotype of the post-depletional T cells has been characterized, little is known about their
function. In the present study, global and CMV-specific T-cell function was assessed
longitudinally in 23 lung transplant (LTx) recipients using T-cell assays (ImmuKnow® and T
Cell Memory™, Cylex, Columbia, MD) during the first year posttransplant after induction …